Influenza Antibody Spray Success: Opens New Approach to Respiratory
Disease Control
MELBOURNE, Australia & NEW YORK (Business Wire EON/PRWEB ) August 21, 2008 --
Anadis Limited (ASX: ANX), a research driven biopharmaceutical company
focused on polyclonal antibodies to address human disease, announced
today important progress concerning its accelerated program to develop a
nasal antibody spray to provide immediate post-exposure prophylaxis
against a range of influenza viruses.
Working with an animal influenza challenge model in the laboratory of
Professor Loreena Brown at the Department of Microbiology and
Immunology, University of Melbourne, scientists successfully completed a
series of proof-in-principal experiments. These experiments using an
animal model designed specifically to test influenza prevention and
treatment, demonstrated the ability of Anadis’
all natural antibody nasal spray formulation to “switch-off”
virus replication at the respiratory tract lining. The studies indicated
a significant impact of single and daily dose of the Anadis polyclonal
antibodies in reducing the likelihood of infection and reducing the
severity of those infected with influenza.
Scientists from the University of Melbourne and Anadis teams are in the
process of submitting data for publication and intend to present the
details at an upcoming influenza control conference.
Anadis CEO Dr. Zeil Rosenberg stated, “Our new
topical spray approach to protecting individuals during seasonal or
epidemic flu outbreaks is a radical new paradigm to protect people from
these influenza viruses. The fact that the Anadis antibodies are all
natural and topically applied means we may have a very safe and
effective new approach to provide immediate protection to all persons
and be able to address multiple virus strains. We know from current
failures in vaccine protection among many persons this past year that
indeed novel approaches like this are urgently needed.”
Anadis VP for Business Development Oren Fuerst further noted, “This
work supports an aggressive commercial strategy expanding our
intellectual property position in this unique area. Our approach shows
for the first time a cost effective method of fighting influenza using
antibodies. We plan to move on our own and with partners to bring this
revolutionary product to market.”
Anadis’ polyclonal antibodies are obtained
using its own proprietary approach to vaccinating dairy cows and then
leveraging advanced dairy industry methods collect first-milking
colostrum under GMP conditions, where it is further formulated as a
spray dried powder, for later reconstitution as an all natural nasal
spray.
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